Cadence
Clinical AI with supervised agents for chronic disease care — 27% fewer admissions, 3:1 Medicare ROI
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About Cadence
Cadence is a clinical AI company founded in 2020 by Chris Altchek in New York that automates the treatment of chronic disease for health systems using supervised AI agents. Serving 90,000+ seniors across 20+ health systems — including Hartford HealthCare and Memorial Hermann — Cadence raised $100M in Series C funding (June 2026) led by Spark Capital at a $1.23B valuation, bringing total funding to $241M.
Cadence is built on the insight that traditional healthcare was designed for episodic visits, not the continuous support that chronic disease management requires. Its supervised AI agents handle the routine, protocol-driven work of chronic care \u2014 medication titration, daily symptom checks, lifestyle coaching, and care coordination \u2014 operating under physician supervision within defined clinical protocols. A nationally licensed clinical team collaborates with each patient's own physician, ensuring every AI-generated alert turns into meaningful clinical action. Cadence operates three care models: 24/7 preventive primary care (covered by Medicare's Advanced Primary Care Management codes), remote patient monitoring based on daily vitals (Medicare RPM codes), and post-acute care to reduce readmissions. Published outcomes show a 27% reduction in hospital admissions, $1,302 lower annual cost per patient, and a 3:1 Medicare ROI — results validated across rural and underserved communities.
Cadence is the right choice for health systems and payers managing large chronic disease populations — particularly those serving Medicare patients with hypertension, heart failure, and diabetes — who need to extend clinical capacity without proportional staff increases, and who want a chronic care AI platform with proven reimbursement pathways and peer-reviewed outcome validation.
Key Features
- Supervised AI agents — automate medication titration, symptom checks, coaching, and care coordination under physician oversight
- 24/7 preventive primary care — Medicare APCM-reimbursable proactive care for chronic disease patients
- Remote patient monitoring — daily vitals tracking with AI-driven trend detection and early intervention alerts
- Post-acute care program — AI-guided care to reduce readmissions following hospital discharge
- Nationally licensed clinical team — collaborates with each patient's physician ensuring every AI alert becomes clinical action
- EHR integration — seamlessly connects with health system existing clinical workflows
- Medicare reimbursement support — RPM and APCM codes supported for qualifying patients
- Care intelligence platform — AI monitors all enrolled patients, identifies risks early, acts before problems escalate
- Population health analytics — dashboards showing chronic care program outcomes and cost savings for health systems
- Hybrid technology + clinical care model — AI amplifies human care teams rather than replacing them
Pros
- Supervised AI agents automate high-volume chronic care tasks under physician oversight — unique clinical AI approach
- $100M Series C (June 2026) at $1.23B valuation — Spark Capital-backed with strong financial momentum
- 27% reduction in hospital admissions, $1,302 lower annual care cost per patient — peer-reviewed outcomes
- 3:1 Medicare ROI published — stronger economic validation than most RPM competitors
- Medicare RPM and APCM reimbursement support — reduces net cost burden on health systems
- Outcomes consistent across rural and underserved communities — proven equity in care access
- Hybrid AI + human clinical team model — AI amplifies clinicians rather than replacing them
Cons
- Enterprise health system sales cycle is long — not accessible to individual practices or small clinics
- No public pricing — all contracts custom negotiated with health systems
- Currently focused on seniors/Medicare population — less suited for younger patient populations
- 90,000+ patient scale is growing but still smaller than Teladoc or Biofourmis
- Dependent on Medicare reimbursement rates — policy changes could impact economics
- AI agents require ongoing physician supervision — not fully autonomous
Pricing
Cadence is an enterprise-only platform with no public pricing. All deployments are custom contracts negotiated directly with health systems and payers.
Many Cadence programs are Medicare-reimbursable: Remote Patient Monitoring (RPM) codes and Advanced Primary Care Management (APCM) codes for qualifying Medicare patients provide a reimbursement pathway that reduces net cost for health systems. Published ROI data shows a 3:1 return to Medicare for every dollar spent.
Contact Cadence through cadence.care for health system partnership and pricing discussions.
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Connect with Cadence
Frequently Asked Questions
Cadence is a clinical AI company that automates the routine, protocol-driven work of chronic care management using supervised AI agents. These agents handle medication titration, symptom checks, lifestyle coaching, and care coordination under physician supervision — allowing health systems to manage far more chronic disease patients than their clinical staff could handle manually.
Cadence uses supervised AI agents — AI that operates within defined clinical protocols under physician oversight. Agents monitor daily vitals, detect trends, trigger timely interventions, and escalate to human clinicians when needed. This hybrid model keeps physicians in control while automating the high-volume, routine tasks of chronic care management.
Cadence operates three care models: 24/7 preventive primary care (covered by Medicare Advanced Primary Care Management codes), remote patient care built on daily vitals monitoring (Medicare RPM codes), and post-acute care focused on reducing hospital readmissions. Most Cadence programs are Medicare-reimbursable for qualifying patients.
Published outcomes include a 27% reduction in hospital admissions, $1,302 lower annual cost of care per patient, and a 3:1 Medicare ROI — meaning Cadence's model returns more than $3 to Medicare for every dollar spent. Results are consistent across rural and underserved communities.
Cadence raised a $100M Series C led by Spark Capital in June 2026, bringing total funding to $241M at a $1.23B valuation. Cadence serves 90,000+ seniors across 20+ health systems including Hartford HealthCare and Memorial Hermann.
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