OpenEvidence
AI clinical decision support free for verified physicians — 757K+ doctors, $12B valuation, peer-reviewed answers
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About OpenEvidence
OpenEvidence is America's leading AI clinical decision support platform \u2014 often described as "ChatGPT for doctors" \u2014 providing verified US physicians with free, instant access to AI-synthesized answers grounded exclusively in peer-reviewed medical literature. Used daily by over 40% of US physicians across 757,000+ verified clinicians and 10,000+ hospitals, OpenEvidence processes 20 million+ clinical consultations per month. In January 2026, it raised $250 million in a Series D round co-led by Thrive Capital and DST Global at a $12 billion valuation.
Unlike general AI tools, OpenEvidence answers only from licensed peer-reviewed content \u2014 with strategic partnerships covering NEJM, JAMA, NCCN, Cochrane, Wiley, and other leading medical publishers. Every answer is sourced and cited, eliminating the hallucination risk that makes general LLMs unsuitable for clinical use. Its product suite spans Medical AI search (free), DeepConsult (multi-step clinical reasoning AI agent), Visits (real-time AI during patient encounters), Voice Mode (hands-free clinical querying), and the AI-Integrated Doctor Dialer (HIPAA-secure communications with embedded clinical AI). In February 2026, Sutter Health became the first publicly announced health system to deploy OpenEvidence inside Epic EHR workflows. The platform withdrew from the EU and UK in April 2026 and is currently US-only.
OpenEvidence is the right choice for US physicians needing fast, reliable, evidence-grounded clinical decision support at the point of care, and for health systems seeking to embed AI-powered medical knowledge directly into their EHR workflows without the hallucination risk of general-purpose AI tools.
Key Features
- Medical AI search — answers clinical questions grounded exclusively in peer-reviewed literature from NEJM, JAMA, NCCN, Cochrane, and Wiley
- DeepConsult — AI agent for multi-step clinical reasoning beyond single-query search responses
- Visits — real-time AI support during patient encounters (launched August 2025)
- AI-Integrated Doctor Dialer — HIPAA-secure calling, messaging, faxing, and voicemail with live clinical AI integrated throughout
- Voice Mode — hands-free voice AI for querying clinical evidence without touching a screen (launched 2026)
- Epic EHR integration — natural-language evidence search embedded directly inside Epic workflows (Sutter Health, Feb 2026)
- Clinical Calculators — integrated clinical scoring tools within the evidence search interface
- Clinical Trials Matching — AI-assisted matching of patients to relevant ongoing clinical trials
- 500M+ clinical studies searchable in seconds across the full peer-reviewed medical literature corpus
- Free access for all verified US physicians — NPI verification required, no subscription cost
Pros
- Free for all verified US physicians — no cost barrier for individual clinician adoption
- 757,000+ verified physicians, 40%+ of US doctors use it daily — most widely adopted clinical AI in the US
- $12B valuation (January 2026), $250M Series D — Thrive Capital and DST Global backed
- Answers grounded exclusively in peer-reviewed literature — zero hallucination risk from non-medical sources
- 20M+ clinical consultations per month — proven real-world clinical usage at unprecedented scale
- Epic EHR integration live at Sutter Health — first public health system embedding of clinical AI in EHR
- DeepConsult AI agent handles multi-step clinical reasoning — goes beyond basic search to structured clinical analysis
Cons
- Withdrew from EU and UK in April 2026 — US-only availability limits international use
- Free tier requires verified NPI number — not accessible to non-US clinicians or students without credentials
- Impact on actual clinical decision-making scored only 1.95/4 in one study — physicians still cautious
- DeepConsult and enterprise features require institutional pricing
- Full chart-aware clinical support (reading patient records proactively) not yet available
- Only 20% of physicians fully support AI in clinical decision-making — adoption barriers remain
Pricing
OpenEvidence is free for all verified US healthcare professionals. NPI verification is required to access the platform. The free tier includes full medical AI search, DeepConsult, Visits, Voice Mode, clinical calculators, and the AI-Integrated Doctor Dialer.
Enterprise pricing applies to health system deployments with EHR integration (Epic), multi-subspecialist AI agents, custom knowledge bases, priority compute, advanced visualization, and API licensing for clinical decision support integration into third-party platforms.
Contact OpenEvidence through openevidence.com for enterprise and health system pricing. Note: The platform withdrew from the EU and UK in April 2026 and is currently available to US healthcare professionals only.
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Frequently Asked Questions
OpenEvidence is free for all verified US physicians and healthcare professionals. You must verify your credentials (NPI number required) to access the platform. Enterprise pricing applies to health system deployments with EHR integration, multi-subspecialist AI agents, and custom knowledge bases.
OpenEvidence answers clinical questions using AI synthesized exclusively from peer-reviewed medical literature — including NEJM, JAMA, NCCN, Cochrane, Wiley, and other leading publishers. Every answer includes citations traceable back to the source literature, eliminating the hallucination risk of general-purpose AI tools like ChatGPT.
DeepConsult is OpenEvidence's first AI agent purpose-built for physicians. It handles multi-step clinical reasoning tasks that go beyond single-query search — synthesizing evidence across multiple questions, comparing treatment options, and generating structured clinical analysis that supports complex decision-making at the point of care.
OpenEvidence serves 757,000+ verified US physicians, processes 20 million+ clinical consultations per month, and is used daily by over 40% of US physicians across 10,000+ hospitals and medical centers. In January 2026, it raised $250M in Series D funding at a $12 billion valuation.
OpenEvidence withdrew from the EU and UK in April 2026 due to regulatory considerations. The platform is currently available only to verified US healthcare professionals. International expansion plans have not been publicly announced.
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